I have stumbled into webcomic Walhalla. Still dizzy from all the lists here. Let me add some comics that I think I haven't seen listed allready. It is a little diverse, you might find something you like.
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Blindsprings (probably known to most), good world building, smooth artstyle, I'd call it fairytale like.
http://blindsprings.com/comic/000 -
Find Chaos If I had to categorize it, it merges sci-fi with the supernatural genre (vamps etc.) The story takes inspiration from both the Bible and literature. (Respecting both) Updates are a little slow and there are gay/lesbian relationships though they are not the main focus.
http://www.findchaos.com/sotfcover-
White Noise, a scifi like webcomic, nice worldbuilding (earth after alien invasion with a twist.) The author is on a small hiatus now because she broke her arm.
http://www.wncomic.com/archive_comments.php?strip_id=2-
Supernormalstep Mentioned before but it deserves to be mentioned again. The story is superb, the art is superb, magic/robots/paralell worlds have to be your thing.
supernormalstep.com
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Dumbing of Age If you are in college or enjoy reading about it, this webcomic is a must, updates every day, awesome right?
http://www.dumbingofage.com/-
Tove Started reading recently, new comic, pretty fun, adventure time like vibes.
http://www.tovecomic.com/index.php?id=1-
Sin Titulo The fact that this is a webcomic and not a published book is madness (and lucky), the style is that of a professional artist (like Minna) with its own flavor, the images tell a story in itself. I cannot summarize the work without discredeting it, I can only say, the story send chills down my spine and it has a surreal/hurts my brain appeal to it. Also, finished.
http://www.sintitulocomic.com/2007/06/17/page-01/-
Bicycle Boy It is about an android who rides a bike in the desert of an apocalyptic world. I love it, just because it is pretty unique. Pretty art.
http://bicycleboy.webcomic.ws/comics/first-
Damsels don't wear glasses The comic is pretty new, and the artstyle is still 'developing'. The premises is still a mysterie, but I was hooked after the maincharacter (red hair, wears glasses) saved a GOAT from a sacrificial ritual by teenage boys in black robes.
http://damsels-dont-wear-glasses.com/?comic_id=1Now I will be reading all the new suggestions from you lovely people here.